Table 1.
Body weight and total plasma cholesterol levels in ND or HD mice in WT and ApoE KO mice
ND/WT | HD/WT | ND/KO | HD/KO | |
---|---|---|---|---|
Body weight (g) | 25.5 ± 0.79 | 30.4 ± 1.21* | 28.4 ± 0.40** | 36.1 ± 0.93* |
Plasma cholesterol (mg/dl) | 118.6 ± 6.1 | 253.9 ± 14.0* | 451.4 ± 73.3* | 885.2 ± 28.4* |
CBF reduction (%) | 85.0 ± 1.2 | 83.7 ± 0.8 | 90.1 ± 1.7** | 87.8 ± 1.7 |
CBF reperfusion (%) | 136.1 ± 6.7 | 121.8 ± 4.9 | 122.9 ± 4.2 | 119.1 ± 10.7 |
Percentage of CBF reduction during ischemia and percentage of CBF reperfusion at 10 min show comparable ischemic severity among groups. Data are expressed as means ± SEM; n = 8–10 per group. *p < 0.01, **p < 0.05, versus ND/WT.