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. Author manuscript; available in PMC: 2011 Feb 16.
Published in final edited form as: Dev Cell. 2010 Feb 16;18(2):237–247. doi: 10.1016/j.devcel.2009.12.014

Figure 5. Cilia defects in bromi mutants.

Figure 5

(A) Neuroepithelial cilia from E10.5 wild-type (WT) and bromi mutant neural tubes analyzed by scanning electron microscopy. bromi mutant cilia showed a swollen or bulbous morphology (arrowheads). (B) Cilia frequency in the wild-type and bromi mutant neuroepithelium. (C) Confocal images of neural tube cilia stained with Arl13b (upper panels), IFT88 and acetylated α-tubulin (lower panels). (D) Neural tube cilia from E10.5 wild-type (WT) and bromi mutant embryos immunostained for γ-tubulin/Arl13b/ Gli2 or γ-tubulin/IFT88/Gli2. Scale bars are 1 μm in A and C and 0.5 μm in D. Error bars in B reflect +/− standard error of the mean.