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. Author manuscript; available in PMC: 2010 Mar 2.
Published in final edited form as: Comput Methods Appl Mech Eng. 2006 Feb 15;195(13-16):1722–1749. doi: 10.1016/j.cma.2005.05.049

Fig. 23.

Fig. 23

A schematic figure of the actomyosin-focal adhesion model. Each actin filament is illustrated as an arrow and its polarity is indicated. The two circular areas represent the focal adhesion sites. The double headed myosin-II motors are assembled into bipolar ‘mini-filaments’ that connect actin-filaments of opposite polarities. The focal adhesion complex will be modeled by quantum or molecular dynamic simulations. The actin filaments will be modeled as coarse-grained elastic rods. The contractile force will be applied onto the focal adhesion complex via atomistic–continuum coupling methods.