Table 3.
Allele frequencies of ATP10A regulatory polymorphisms
| Promoter SNPs | Intron SNPs | |||||
|---|---|---|---|---|---|---|
| rs2076748 (A/G) |
rs4906796 (C/G) |
rs2076749 (T/A) |
rs4906777 (A/G) |
rs4566129 (T/C) |
Gender (M/F) |
|
| Monoallelic | A 1 (5) | C 0.8 (5) | T 0.5 (3) | A 0.83 (6) | T 0.67 (6) | M 0.14 (7) |
| G 0 | G 0.2 | A 0.5 | G 0.17 | C 0.33 | F 0.86 | |
| Biallelic | A 0.6 (5) | C 0.7 (5) | T 0.67 (4) | A 0.59 (11) | T 0.41(11) | M 0.82 (11) |
| G 0.4 | G 0.3 | A 0.33 | G 0.41 | C 0.59 | F 0.18 | |
| P value | 0.087 | 1 | 0.58 | 0.252 | 0.282 | 0.013 |
Numbers in parentheses indicate the number of individuals genotyped for each polymorphism
P values represent comparison of each SNP or gender between monoallelic and biallelic ATP10A expression categories using Fisher’s exact test.