Figure 1.

HKBA induces astrogliosis in the striatum of BALB/c mice. Mice received an intracranial injection of HKBA (1 × 10⁶ bacteria) or vehicle solution (PBS). After 24 hours animals were sacrificed and striatum sections were subjected to immunostaining with anti-GFAP Ab (A) or with cresyl violet (B), and digital images close to or distant from the injection site were taken by confocal microscopy. Representative images revealed astrogliosis (A) and neutrophil infiltrate (B, arrows) in animals treated with HKBA, but not in PBS-treated ones. Scale bar = 50 μm.