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. 2010 Mar 1;5(3):e9466. doi: 10.1371/journal.pone.0009466

Table 3. Number of genes and independent publications with selected prognostic categories.

Tag (total genes) (total references) No. genes in 1 study No. genes in 2 studies No. genes in 3 studies No. genes in 4 studies No. genes in 5 studies No. genes in 6 studies No. genes in 7 studies No. genes in 8 studies
poor prog (1727) (12) all genes 1559 138 27 3
up-regulated 586 28 2
down-regulated 943 55 10 1
good prog (1638) (11) all genes 1484 134 18 1 1
up-regulated 925 62 9 1
down-regulated 528 24 2
NPM1 mut (1169) (5) all genes 978 147 32 11 1
up-regulated 541 42 18 7 1
down-regulated 436 96 13 2
t(15;17) (230) (9) all genes 188 25 9 7 1
up-regulated 115 17 5 6
down-regulated 56 8 4 1 1
inv(16) (1322) (9) all genes 1197 88 23 7 6 1
up-regulated 533 44 12 7 2 1
down-regulated 285 15 4 1
t(8;21) (1195) (9) all genes 1057 92 23 15 4 1 2 1
up-regulated 253 32 13 4 1 2 1
down-regulated 552 27 5 2
11q23 (482) (5) all genes 459 19 4
up-regulated 65 1
down-regulated 45 3
FLT3-ITD (235) (4) all genes 224 10 1
up-regulated 135 2
down-regulated 67
normal cyto (519) (6) all genes 480 36 3
up-regulated 173 1
down-regulated 206 6

The AML prognosis and subtype identification tags reported in greater than 3 independent studies are shown with the number of genes listed by number of independent studies and differential expression direction. Identification tag descriptions can be found in Table S1. Note that the following tags are abbreviated: poor prog is poor prognosis, good prog is good prognosis, NPM1 mut is NPM1 mutation, and normal cyto is normal cytogenetics.