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. 2010 Jan 25;11:46. doi: 10.1186/1471-2105-11-46

Table 2.

Clusters of structurally similar proteins.

Cluster Size Degrees GO Terms enriched (Molecular Function, "MF")
Cluster 1 16 22-56 GO:0000739 DNA strand annealing activity
GO:0003682 chromatin binding
GO:0003746 translation elongation factor activity
GO:0004145 diamine N-acetyltransferase activity
GO:0004157 dihydropyrimidinase
GO:0004864 protein phosphatase inhibitor activity
GO:0016455 RNA polymerase II transcription mediator activity
GO:0018024 histone-lysine N-methyltransferase activity
GO:0050681 androgen receptor binding

Cluster 2 32 8-20 GO:0008270 zinc ion binding

Cluster 3 86 4-7 GO:0003899 DNA-directed RNA polymerase activity
GO:0005125 cytokine activity
GO:0019900 kinase binding
GO:0042562 hormone binding

Cluster 4 131 2-3 GO:0003777 microtubule motor activity
GO:0005088 Ras guanyl-nucleotide exchange factor activity

Cluster 5 136 1 GO:0003700 transcription factor activity
GO:0003723 RNA binding
GO:0003779 actin binding
GO:0005198 structural molecule activity

Table 2 presents the groups of proteins obtained by clustering the respective sociality parameters. The number of proteins in each cluster, their degrees and molecular functions found by GO-significance analysis are displayed.