Figure 5.

Genomic alignment of species at the R/G site of gluR-B. A 17-species alignment, visualized with TeXshade [49], of the genomic region overlapping gluR-B at the R/G editing site. The column corresponding to the edited site is shown in red, while the complementary site is shown in orange. The loop is shown in grey. We note: (1) extreme conservation, (2) lost conservation in Tetraodon, (3) the A-G mutation occurring in Tetraodon in the edited column. The green rectangle surrounds a 21-column window used as an example in Methods.