Table 2.
Genes regulated by factor VIIa (FVIIa) (P < 0.01 and more than 2-fold) as well as protease-activated receptor 2 (PAR2) agonist peptide in MDA-MB231 cells exposed to the agonist for 1 h
| Acc# | Annotation | FVIIa/ media 1 h |
FVIIa/ PAR1 1 h |
FVIIa/ PAR2 1 h |
Category | FVIIa regulation verified by qPCR |
|---|---|---|---|---|---|---|
| NM_001511 | Chemokine (C-X-C motif) ligand 1 (CxcL1). melanoma growth stimulating activity. alpha (Groα) | 20.65 | 12.73 | 1.95 | Chemokines cytokines, growth factors | Yes |
| M26383 | Interleukin 8 (IL-8) | 6.41 | 8.14 | 1.22 | Yes | |
| M11220 | Granulocyte-macrophage colony stimulating factor (GM-CSF) (csf2) | 6.39 | 4.51 | 0.91 | Yes | |
| NM_002211 | Integrin. beta 1 | 2.62 | 2.52 | 0.82 | Cell adhesion, matrix modeling | No |
| BC037420 | Baculoviral IAP (Inhibitor of apoptosis domain) repeat-containing 3 (Birc3) | 3.03 | 3.26 | 1.07 | Apoptosis |