Figure 4. Spastin is essential for photoreceptor morphogenesis in the mid-stage developing pupal eyes.

(A, B) Pupal eyes (45% pupal stage) with spastin^5.75 null mutant clones marked by the absence of the GFP (green). Acetylated tubulin (Acetub, red) was decreased or destabilized in the absence of the spastin. Crb (blue) is mislocalized at the distal section (A, arrows) and almost absent at the proximal section (B, arrow-heads) from the same pupal eye. (C) Developing pupal photoreceptors elongate from distal to proximal direction. Distal (A) and proximal (B) sections were marked by dashed-lines.