Table 2. Comparison of organ weights from outbred and congenic collagen X mice.
| Organ Weights | ||||||
| Outbred WT | C57BL/6 | DBA/2J | ||||
| Body | 9.24±0.22 (15) | 8.81±0.21 (43) | 8.15±0.25 (48) | |||
| Kidney | 72.10±1.76 (16) | 61.42±1.28 (43) | 64.60±2.06 (50) | |||
| Kidney:Body | 128∶1 (15) | 143∶1±2 (43) | 128∶1±1 (48) | |||
| Spleen | 79.33±7.44 (10) | 61.76±2.78 (43) | 75.68±3.64 (50) | |||
| Thymus | 37.31±1.46 (15) | 55.72±1.42 (43) | 38.97±1.37 (50) | |||
| Kidney:Spleen | 0.90∶1 (10) | 0.99∶1±0.04 (43) | 1.14∶1±0.04 (50) | |||
| Kidney:Thymus | 0.52∶1 (15) | 0.91∶1±0.02 (43) | 0.60∶1±0.01 (50) | |||
| Outbred Tg | C57BL/6 Tg | DBA/2J Tg | Outbred Tg severe | C57/Bl6 Tg severe | DBA/2J Tg severe | |
| Body | 7.34±0.31 (7) | 6.64±0.22 (21) | 6.85±0.22 (19) | 4.74±0.14 (45) | 3.47±0.36 (5) | 3.81±0.16 (8) |
| Kidney | 56.09±2.32 (7) | 48.3±1.6 (21) | 52.64±1.42 (19) | 38.49±1.05 (46) | 25.74±4.48 (5) | 33.56±2.82 (8) |
| Kidney:Body | 131∶1 (7) | 138∶1±2 (21) | 130∶1±2 (19) | 123∶1 (45) | 140∶1±11 (5) | 117∶1±6 (8) |
| Spleen | 31.38±2.63 (7) | 30.8±2.4 (21) | 50.35±3.24 (19) | 9.06±0.50 (47) | 6.74±0.75 (5) | 9.33±1.51 (8) |
| Thymus | 37.06±1.89 (7) | 34.7±1 (21) | 32.74±1.43 (19) | 8.50±0.68 (47) | 3.42±0.58 (5) | 7.98±1.60 (8) |
| Kidney:Spleen | 0.57∶1 (7) | 0.62∶1±0.03 (21) | 1.14∶1±0.04 (19) | 0.23∶1 (46) | 0.29∶1±0.06 (5) | 0.28∶1±0.04 (8) |
| Kidney:Thymus | 0.66∶1 (7) | 0.73∶1±0.02 (21) | 1.24∶1±0.13 (19) | 0.22∶1 (46) | 0.14∶1±0.02 (5) | 0.24∶1±0.04 (8) |
| Outbred KO | C57BL/6 KO | DBA/2J KO | Outbred KO severe | C57/Bl6 KO severe | DBA/2J Tg severe | |
| Body | 8.41±0.17 (33) | 8.68±0.20 (50) | 8.68±0.17 (50) | 5.40±0.27 (10) | 3.96±0.30 (4) | 3.58 (1) |
| Kidney | 61.66±1.60 (41) | 58.74±1.17 (50) | 63.16±1.35 (50) | 45.69±2.35 (13) | 31.98±1.97 (4) | 40.70±14.50 (2) |
| Kidney:Body | 141∶1 (33) | 148∶1±2 (50) | 138∶1±1 (50) | 118∶1 (10) | 123∶1±4 (4) | 137∶1 (1) |
| Spleen | 58.73±3.71 (44) | 64.38±2.62 (50) | 77.41±2.91 (50) | 10.12±1.12 (10) | 9.43±1.41 (4) | 4.3 (1) |
| Thymus | 48.58±2.23 (40) | 59.41±1.23 (50) | 45.37±1.15 (50) | 8.52±1.35 (12) | 6.88±1.14 (4) | 5.55±0.45 (2) |
| Kidney:Spleen | 0.95∶1 (41) | 1.09∶1±0.04 (50) | 1.21∶1±0.05 (50) | 0.22∶1 (10) | 0.29∶1±0.03 (4) | 0.164∶1 (1) |
| Kidney:Thymus | 0.79∶1 (40) | 1.01∶1±0.01 (50) | 0.72∶1±0.01 (50) | 0.19∶1 (12) | 0.21∶1±0.03 (4) | 0.152∶1 (2) |
Body and organ weights of spleen, both thymic lobes, and the left kidney from outbred and congenic (C57Bl/6 and DBA/2J) control (WT), collagen X transgenic (Tg), null (KO), and perinatal lethal (Tg severe or KO severe) mice show conservation of weight trends across all strains. Numbers in parenthesis indicate the number of animals analyzed.