Fig. 4.

Bipolar and horizontal cells extend dendritic processes into the ONL in the nob2 but not WT retina. Retinal sections from WT (a, c, & e) or nob2 (b, d, & f) retinas immunolabeled with antibodies against the rod bipolar cell marker, PKCα (a & b), the horizontal cell marker, calbindin (c & d), or the HBC marker NK3R (e &f). INL, inner nuclear layer; OPL, outer plexiform layer; and ONL, outer nuclear layer. DIC images were obtained from a WT retina. Scale bar indicates 20 μm. Mice were studied at 5 months of age.