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. Author manuscript; available in PMC: 2011 Mar 1.
Published in final edited form as: Clin Cancer Res. 2010 Feb 23;16(5):1478–1485. doi: 10.1158/1078-0432.CCR-09-1531

Figure 1. Effect of Lestaurtinib on TrkB autophosphorylation induced by BDNF.

Figure 1

A. The SY5Y-TrkB neuroblastoma line was exposed to BDNF in the absence and presence of increasing concentrations of Lestaurtinib. Maximal inhibition of ligand-induced autophosphorylation was seen by 100-200 nM. B. Densitometry of phospho-Trk relative to total Trk for each of the conditions in Fig. 1A.