. Author manuscript; available in PMC: 2011 Mar 9.

Published in final edited form as: Biochemistry. 2010 Mar 9;49(9):2075–2085. doi: 10.1021/bi902222s

TABLE 1.

The cysteine residues in TbQSOX



Cysteine Residue	Motif	Corresponding cysteines in related proteins
Trx domain
58	n/a	not conserved
69, 72	C^I-C^II	C⁷⁰ – C⁷³ (CxxC_trx) of human QSOX1b; C⁶¹ – C⁶⁴ of yeast Pdi1p
105, 112	Cx₆C	C¹⁰¹ – C¹¹⁰ (Cx₈C) of human QSOX1b; C⁹⁰ – C⁹⁷ (Cx₆C) of yeast Pdi1p
132, 138	Cx₅C	not conserved

HRR domain
180	n/a	not conserved

Erv/ALR domain
305, 317	Cx₁₁C	Unique to QSOX family; C³⁹³ – C⁴⁰⁵ (Cx₁₁C) of human QSOX1b
350, 353	C^III-C^IV	C⁴⁴⁹ – C⁴⁵² (CxxC_prox) of human QSOX1b; C¹²¹ – C¹²⁴ of yeast Erv2p
405, 408	C^V-C^VI	C⁵⁰⁹ – C⁵¹² (CxxC_trm) of human QSOX1b; C¹⁷⁶ – C¹⁷⁸ of yeast Erv2p