Figure 1.
Modeling of LINE1 methylation deciles and corresponding risk of bladder cancer. LINE1 methylation decile bins are represented on the x-axis, and corresponding risk, modeled as odds ratios represented on the y-axis, of bladder cancer adjusting for smoking, age and gender using logistic regression. The black horizontal line depicts the odds ratio point estimate at each LINE1 methylation decile, compared to the referent highest decile. The gray bar represents the range of the 95% upper and lower confidence intervals. Below each decile bin on the x-axis are the number of observations present at each decile LINE1 methylation level. The deciles were coded based on the distribution in controls and range from 67 to 86 observations.