Table 1.
Selected Characteristics of bladder cancer cases and controls with LINE1 methylation data
| Variable | Total N=750 (%) |
Controls N=465 (62.0%) |
Cases N=285 (38.0%) |
|---|---|---|---|
| Sex (N=750) | |||
| Male | 521 (69.5%) | 297 (63.9%) | 224 (78.6%) |
| Female | 229 (30.5%) | 168 (36.1%) | 61 (21.4%) |
| Smoking status (N=750) | |||
| Never | 194 (25.9%) | 140 (30.1%) | 54 (19.0%) |
| Former | 382 (50.9%) | 240 (51.6%) | 142 (49.8%) |
| Current | 174 (23.2%) | 85 (18.3%) | 89 (31.2%) |
| Carcinoma Severity (N=730) | |||
| Non-invasive | 194 (68.1%) | -- | 194 (68.1%) |
| Invasive | 71 (24.9%) | -- | 71 (24.9%) |
| Missing | 20 (7.0%) | -- | 20 (7.0%) |
| Toenail arsenic (N=733) | |||
| 0.01 to <0.06: 0-25% | 179 (23.9%) | 110 (23.7%) | 69 (24.2%) |
| 0.059 to <0.09: 25.1-50% | 201 (26.8%) | 120 (25.8%) | 81 (28.4%) |
| 0.09 to <0.13: 50.1-75% | 180 (24.0%) | 116 (25.0%) | 64 (22.5%) |
| 0.13 to <0.20: 75.1-90% | 104 (13.9%) | 69 (14.8%) | 35 (12.3%) |
| 0.20 to 2.48: 90.1-100% | 69 (9.2%) | 40 (8.6%) | 29 (10.2%) |
| Missing | 17 (2.3%) | 10 (2.2%) | 7 (2.5%) |
| Age | |||
| Mean (+/-SD) | 62.2 (10) | 61.7 (10.4) | 63.1 (9.4) |