Table 1.
Drinking 30% Sucrose ad lib has similar restorative effects to supplying replacement corticosterone in adrenalectomized rats, compared to shamadrenalectomized controls.
| Adrenalectomy | Adrenalectomy + 30% sucrose |
Adrenalectomy + corticosterone |
|
|---|---|---|---|
| In the CNS: | |||
| CRF in the CeA | Decreased | Normal | Normal |
| CRF in the PVN | Increased | Normal | Normal |
| DBH in the LC* | Decreased | Normal | Normal |
| In the Periphery: | |||
| Insulin | Decreased | Normal | Normal |
| Fat depot weight | Decreased | Normal | Normal |
*
DBH = norepinephrine-synthesizing enzyme, dopamine B-hydroxylase, in the brainstem locus coeruleus