Table 3.
Factors significantly associated with local recurrence in multivariable regression analysis in addition to age and preinvasive or in situ (stage 0) carcinoma
| Variable | Hazard ratio* (95% CI) | P value |
|---|---|---|
| Interval >6 weeks: | 1.19 (1.01 to 1.39) | 0.033 |
| Age (per each additional year of age) | 0.99 (0.98 to 1.01) | 0.198 |
| Hispanic: | ||
| No | 1.0 (reference) | 0.006 |
| Yes | 1.61 (1.14 to 2.27) | |
| Tumour grade: | ||
| Low | 1.0 (reference) | <0.001 |
| Intermediate | 1.39 (1.12 to 1.73) | |
| High | 1.75 (1.37 to 2.23) | |
| Unknown | 1.52 (1.19 to 1.95) | |
| Progesterone receptor status: | ||
| Positive | 1.0 (reference) | 0.014 |
| Negative | 1.37 (1.13 to 1.66) | |
| Borderline | 1.67 (0.79 to 3.53) | |
| Unknown | 1.04 (0.85 to 1.27) | |
| Histology: | ||
| Ductal | 1.0 (reference) | 0.010 |
| Lobular | 1.00 (0.75 to 1.35) | |
| Mixed ductal/lobular | 1.07 (0.78 to 1.48) | |
| Tubular/medullary/mucinous/papillary | 1.26 (0.97 to 1.63) | |
| Unspecified adenocarcinoma | 1.61 (1.24 to 2.08) | |
| Other histology | 0.83 (0.48 to 1.46) | |
| Preinvasive or in situ (stage 0) carcinoma: | ||
| No | 1.0 (reference) | 0.419 |
| Yes | 1.11 (0.86 to 1.42) | |
| Year (per each later year of diagnosis) | 0.95 (0.92 to 0.97) | <0.001 |
| Laterality: | ||
| Right | 1.0 (reference) | 0.016 |
| Left | 1.20 (1.03 to 1.38) | |
*Adjusted for each of the variables presented in table.