Table 3.
Regression coefficient and (p) values of significant phenotypic correlations between the expressions of the enzymes analyzed. The phenotypical correlations were decomposed in terms of genetic and environmental correlations. All significant correlations were positive and are highlighted.
| Phenotype | TxAS-expression | mPGES-1-expression | COX-2-expression |
|---|---|---|---|
| COX-1-expression | 0.21(0.002) | 0.18(0.038) | 0.25(0.002) |
| COX-1-expression-genetic | 0.13(0.464) | 0.27(0.167) | 0.29(0.121) |
| COX-1-expression-environmental | 0.36(0.037) | 0.10(0.530) | 0.22(0.247) |
| COX-2-expression | 0.46(2.42·10−11) | 0.27(2.75·10−5) | |
| COX-2-expression-genetic | 0.45(9.47·10−4) | 0.30(0.020) | |
| COX-2-expression-environmental | 0.49(0.025) | 0.21(0.226) | |
| mPGES-1-expression | 0.53(5.6·10−14) | ||
| mPGES-1-expression-genetic | 0.70(3.25·10−7) | ||
| mPGES-1-expression-environmental | 0.27(0.107) | ||