Table 1.
Drugs Used in the Treatment of HIV Infection [5]
| Brand Name | Generic Name | Manufacturer Name | Approval Date |
|---|---|---|---|
| A | |||
| Combivir* | lamivudine and zidovudine | GlaxoSmithKline | 27-Sep-97 |
| Emtriva | emtricitabine, FTC | Gilead Sciences | 02-Jul-03 |
| Epivir*# | lamivudine, 3TC | GlaxoSmithKline | 17-Nov-95 |
| Epzicom | abacavir and lamivudine | GlaxoSmithKline | 02-Aug-04 |
| Hivid | zalcitabine, dideoxycytidine, ddC | Hoffmann-La Roche | 19-Jun-92 |
| Retrovir*# | zidovudine, azidothymidine, AZT, ZDV | GlaxoSmithKline | 19-Mar-87 |
| Trizivir | abacavir, zidovudine, and lamivudine | GlaxoSmithKline | 14-Nov-00 |
| Truvada | tenofovir disoproxil fumarate and emtricitabine | Gilead Sciences, Inc. | 02-Aug-04 |
| Videx EC | enteric coated didanosine, ddI EC | Bristol Myers-Squibb | 31-Oct-00 |
| Videx*# | didanosine, dideoxyinosine, ddI | Bristol Myers-Squibb | 9-Oct-91 |
| Viread* | tenofovir disoproxil fumarate, TDF | Gilead | 26-Oct-01 |
| Zerit* | stavudine, d4T | Bristol Myers-Squibb | 24-Jun-94 |
| Ziagen | abacavir sulfate, ABC | GlaxoSmithKline | 17-Dec-98 |
| (generic version) | Didanosine (ddI)Delayed Release capsules | Barr Lab. | 3-Dec-04 |
| B | |||
| Intelence | etravirine | Tibotec Therapeutics | 18-Jan-08 |
| Rescriptor | delavirdine, DLV | Pfizer | 4-Apr-97 |
| Sustiva*# | efavirenz, EFV | Bristol Myers-Squibb | 17-Sep-98 |
| Viramune*# | nevirapine, NVP | Boehringer Ingelheim | 21-Jun-96 |
| C | |||
| Agenerase | amprenavir, APV | GlaxoSmithKline | 15-Apr-99 |
| Aptivus | tipranavir, TPV | Boehringer Ingelheim | 22-Jun-05 |
| Crixivan*# | indinavir, IDV, | Merck | 13-Mar-96 |
| Fortovase | saquinavir (no longer marketed) | Hoffmann-La Roche | 7-Nov-97 |
| Invirase | saquinavir mesylate, SQV | Hoffmann-La Roche | 6-Dec-95 |
| Kaletra*# | lopinavir and ritonavir, LPV/RTV | Abbott Laboratories | 15-Sep-00 |
| Lexiva | Fosamprenavir Calcium, FOS-APV | GlaxoSmithKline | 20-Oct-03 |
| Norvir | ritonavir, RTV | Abbott Laboratories | 1-Mar-96 |
| Prezista | darunavir | Tibotec, Inc. | 23-Jun-06 |
| Reyataz* | atazanavir sulfate, ATV | Bristol-Myers Squibb | 20-Jun-03 |
| Viracept* | nelfinavir mesylate, NFV | Agouron Pharmaceuticals | 14-Mar-97 |
| D | |||
| Fuzeon | enfuvirtide, T-20 | Hoffmann-La Roche & Trimeris | 13-Mar-03 |
| E | |||
| Selzentry | maraviroc | Pfizer | 06-August-07 |
| F | |||
| Isentress | raltegravir | Merck & Co., Inc. | 12--Oct-07 |
| G | |||
| Atripla | efavirenz, emtricitabine and tenofovir disoproxil fumarate | Bristol-Myers Squibb and Gilead Sciences | 12-July-06 |
(A)
Nucleoside reverse transcriptase inhibitors (NRTIs);
(B)
Nonnucleoside reverse transcriptase inhibitors (NNRTIs);
(C)
Protease inhibitors (PIs);
(D)
Fusion inhibitors;
(E)
Entry Inhibitors - CCR5 co-receptor antagonist;
(F)
HIV integrase strand transfer inhibitors;
(G)
Multi-class Combination Products.
*
Available in Chinese market
#
free drugs provided by the government.