Table 3.
Adjusted and unadjusted correlations between pulse wave analysis parameters and carotid intima-media thickness
| Correlation coefficient | P value | Unadjusted regression coefficient | P value | Model 1 | Model 2 | ||||
|---|---|---|---|---|---|---|---|---|---|
| Adjusted regression coefficienta | P value | Adjusted regression coefficientb | P value | ||||||
| 1 | C_PP | 0.36 | P ≤ 0.0001 | 0.004 (0.003–0.005) | P ≤ 0.0001 | 0.0025 (0.001–0.004) | P ≤ 0.0001 | 0.0025 (0.002–0.004) | P ≤ 0.0001 | 
| 2 | C_SP | 0.29 | P ≤ 0.0001 | 0.003 (0.002–0.004) | P ≤ 0.0001 | 0.0017 (0.0009–0.0025) | P ≤ 0.0001 | 0.0017 (0.0009–0.0026) | P ≤ 0.0001 | 
| 3 | C_AGPH | 0.17 | P = 0.001 | 0.002 (0.001–0.004) | P = 0.001 | 0.0007 (−0.0007 to 0.0021) | P = 0.31 | 0.0007 (−0.0007 to 0.0022) | P = 0.31 | 
| 4 | AMPR | −0.21 | P ≤ 0.0001 | −0.12 (−0.17 to −0.06) | P ≤ 0.0001 | −0.072 (−0.1234 to −0.0207) | P = 0.01 | −0.073 (−0.1241 to −0.0211) | P = 0.01 | 
| 5 | BR_PP | 0.32 | P ≤ 0.0001 | 0.003 (0.002–0.004) | P ≤ 0.0001 | 0.0017 (0.0007–0.0027) | P = 0.001 | 0.0018 (0.0008–0.0028) | P = 0.001 | 
AMPR, amplification ratio; BR_PP, brachial pulse pressure; C_PP, aortic pulse pressure; C_SP, central aortic systolic pressure.
Regression analysis adjusted for age, gender, and race. Diabetes, hypertension, hemoglobin, parathyroid hormone, total cholesterol, high-density lipoprotein, and triglycerides were included in the initial model but were not significant in a multivariable adjusted model.
Regression analysis adjusted for age, gender, race, and β-blocker use.