Table 2.
Age-Adjusted Means of Marker Scores in Cerebral Cortical Neurons in PVL and Control Cases
Age-adjusted mean (SE) | p-value | ||||
---|---|---|---|---|---|
PVL | Controls | PVL v. Controls | PCA | Interaction DX × PCA | |
MDA | 0.65 (0.14) | 0.06 (0.12) | 0.005 | NS | NS |
HNE | 1.23 (0.15) | 0.00 (0.13) | NS | NS | 0.024 |
NT | 0.20 (0.09) | 0.00 (0.07) | 0.091 | NS | NS |
GFAP | 0.97 (0.26) | 0.39 (0.22) | 0.100 | 0.099 | NS |
CD68 | 0.73 (0.15) | 0.33 (0.13) | 0.060 | 0.082 | NS |
SE = standard error of the mean; PCA = postconceptional age; DX = diagnosis (PVL vs. control); NS = not significant and p > 0.100; p values ≥0.05 and <0.100 are included to indicate possible trends for future study; bold type = p value <0.050; − = not applicable. Range of marker scores is 0 (no staining) to 3 (>20 positive cells/high-power field) (see text for details). Ages of analyzed cases are 34 to 109 postconceptional weeks (see text for details).