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. Author manuscript; available in PMC: 2010 Apr 2.
Published in final edited form as: Biochem Biophys Res Commun. 2009 Jul 15;387(4):656–660. doi: 10.1016/j.bbrc.2009.07.045

Fig. 2.

Fig. 2

Phosphorylation of H2AX following treatment with medium containing 300 μM TMZ for 3 h in Lig4+/+ cells (open columns) or Lig4−/− cells (close columns) at the indicated time points. The relative inducible γH2AX levels at different time points were normalized against the γH2AX levels measured immediately after treatment. For each cell line, the value of the γH2AX levels measured immediately after treatment was set as 100. Columns show the means of at least three independent experiments; the bars indicate the SD. *, Difference is statistically significant (P < 0.05).