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Cytochrome P-450 ω-hydroxylase and epoxygenase activity in microsomes prepared from the hearts of diabetic and non-diabetic rats: (a) 20-HETE formation was significantly elevated in microsomes prepared from the hearts of diabetic rats as compared to the non-diabetic animals; (b) DiHETEs and EETs formation were not different between diabetic and non-diabetic rats. Mean ± SEM (n = 5). *Significantly different compared to untreated control, P < 0.05.
