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Effect of HET0016 (0.01, 0.1 and 1.0 μM) on (a) % recovery in Pmax and (b) LVEDP in perfused hearts of control and diabetic rats. Effect of combination treatment with HET0016 (0.1 μM) and glibenclamide (1 μM) was investigated in hearts from diabetic rats only. Mean ± SEM (n = 5). *Significantly different compared to untreated control, #Significantly different compared to untreated-STZ, §Significantly different compared to STZ-HET0016, P < 0.05.
