Table 2.
The nucleocytosolic locations of transcripts and the presence of miRNA target sites
| With miRNA target site(s) | Without miRNA target site(s) | P-value | |
|---|---|---|---|
| Total | 65 398 | 60 862 | |
| HepG2: cytosol | 3883 | 3018 | 8.62 × 10−15 |
| HepG2: nucleus | 2991 | 4599 | 1.00 |
| HeLa: cytosol | 6121 | 4018 | 1.49 × 10−73 |
| HeLa: nucleus | 4378 | 7151 | 1.00 |
| Both: cytosol | 1747 | 897 | 2.59 × 10−51 |
| Both: nucleus | 1053 | 1894 | 1.00 |
Among the 126 260 transcript isoforms assembled from databases, 65 398 of them contain a possible miRNA target site. ‘HepG2: cytosol’ means the cytosolic isoforms in HepG2 cells. The same applies to the other groups. The counts of the transcript isoforms with or without miRNA target sites are listed. The P-value is the probability of randomly drawing the same or higher number of transcript isoforms with miRNA target sites. It was calculated based on the hypergeometric test.