Table 1.
Baseline characteristics of infants exposed to oxygen through the initial 24 hours of age and those not exposed
| Variable | O2 requirement continuously from 6 to 24 hours N(%) or mean (SD) N=729 |
O2 exposure< 6 hours N (%) or mean (SD) N=330 |
P value (Fisher’s exact test or linear regression) |
|---|---|---|---|
| Birth weight (grams) | 747 (141) | 793 (134) | <0.001 |
| Gestational age (weeks) | 26 (1.8) | 27 (2.1) | <0.001 |
| SGA | 77 (11%) | 73 (22%) | <0.0001 |
| Gender – Male | 363 (50%) | 151 (46%) | 0.23 |
| Race – Black | 346 (47%) | 158 (48%) | 0.95 |
| AN steroids | 540 (74%) | 262 (80%) | 0.05 |
| Maternal antibiotics in the admission resulting in the delivery | 509 (70%) | 218 (67%) | 0.31 |
| 5 min Apgar< 5 | 105 (15%) | 34 (11%) | 0.08 |
| DR FiO2 (oxygen) | 721 (99%) | 323 (98%) | 0.15 |
| DR intubation | 570 (78%) | 228 (69%) | 0.002 |
| RDS | 717 (98%) | 276 (84%) | <0.001 |
| Any Surfactant | 645 (88%) | 217 (66%) | <0.001 |
| Surfactant doses | 2.0 (1.0) | 1.5 (0.8) | <0.001 |
| High frequency ventilation in the 1st 24 hours | 39 (5%) | 9 (3%) | 0.06 |
| Early onset sepsis | 14 (2%) | 2 (1%) | 0.17 |
| Antibiotics ≥ 5 days | 391 (54%) | 135 (41%) | 0.002 |
DR delivery room
RDS Respiratory distress syndrome