Table 1.

Examples of drugs studied using allergen inhalation challenge

^*True positives are those drugs which modify the challenge and have been shown to be effective in asthma; ^†True negatives are drugs which did not modify allergen challenge and which have failed in larger clinical trials of asthma patients; ^‡False positives are drugs which modified the challenge, but which are not useful to treat asthma; ^§False negatives would be drugs which did not modify the challenge, but are useful to treat asthma.

No false negatives have been identified to date.

ICS, inhaled corticosteroids; LABA, long acting β₂-agonists; SABA, short acting β₂-agonists; Anti-LT, anti-leukotrienes; PAF, platelet activating factor; PGE, prostaglandin E.