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. 2010 Mar 9;182(4):333–340. doi: 10.1503/cmaj.091080

Table 4.

Sensitivity analysis of the effect of helmet use on head injuries

Parameter No. of studies OR (95% CI) Heterogeneity, I2 value, %
Methodologic quality*
 High (score ≥ 18) 6 0.68 (0.55–0.82) 75.8
 Low (score < 18) 4 0.59 (0.35–1.00) 73.1
Study design
 Case–control 9 0.66 (0.55–0.79) 75.7
 Cohort 1 0.48 (0.48–0.34) NA
Adjusted for confounding
 Yes 6 0.68 (0.55–0.82) 75.8
 No 4 0.59 (0.35–1.00) 73.1
Adequate outcome assessment
 Yes 9 0.69 (0.58–0.82) 69.3
 No 1 0.43 (0.29–0.64) NA
Adequate exposure assessment
 Yes 7 0.66 (0.54–0.79) 74.0
 No 3 0.63 (0.30–1.34) 79.7
Adequate selection of cases and controls
 Yes 8 0.66 (0.54–0.79) 70.0
 No 2 0.66 (0.29–1.49) 89.6

Note: CI = confidence interval, NA = not applicable, OR = odds ratio.

*

Overall scores for methodologic quality were determined with use of the Downs and Black checklist (maximum score 28).28