TABLE 1.
Length of time for CDR recommendations, by year of recommendation*
| Generic drug name (brand name) | CDR submission | CDR recommendation | Time lapse (weeks) | σ |
|---|---|---|---|---|
| dutasteride (Avodart®) | 24/08/2004 | 20/01/2005 | 21.3 | |
| adalimumab (Humira® – rheumatoid arthritis) | 24/09/2004 | 11/02/2005 | 20.0 | |
| abacavir/lamivudine (Kivexa®) | 26/07/2005 | 07/12/2005 | 19.1 | |
| mycophenolate sodium (Myfortic®) | 03/03/2005 | 08/07/2005 | 18.1 | |
| erlotinib (Tarceva®) | 19/07/2005 | 07/12/2005 | 20.1 | |
| fosamprenavir calcium (Telzir®) | 24/01/2005 | 16/06/2005 | 20.4 | |
| voriconazole (Vfend® – aspergillus) | 25/10/2004 | 14/04/2005 | 24.4 | |
| drospirenone / ethinyl estradiol (Yasmin®) | 20/01/2005 | 16/06/2005 | 21.0 | |
| Median | 20.3 | 1.9 | ||
| niacin / lovastatin (Advicor®) | 18/10/2005 | 26/04/2006 | 27.1 | |
| ciclesonide (Alvesco®) | 24/07/2006 | 20/12/2006 | 21.3 | |
| tipranavir (Aptivus®) | 25/12/2005 | 17/05/2006 | 20.4 | |
| amlodipine besylate / atorvastatin calcium (Caduet®) | 25/12/2005 | 17/05/2006 | 20.4 | |
| travoprost and timolol maleate (Duotrav®) | 24/03/2006 | 24/08/2006 | 21.9 | |
| adalimumab (Humira® – psoriatic arthritis) | 21/06/2006 | 29/11/2006 | 23.0 | |
| quinagolide hydrochloride (Norprolac®) | 23/11/2005 | 17/05/2006 | 25.0 | |
| etonogestrel / ethinyl estradiol (Nuvaring®) | 05/05/2006 | 29/11/2006 | 29.7 | |
| pantoprazole magnesium (Pantoloc M®) | 17/03/2006 | 20/07/2006 | 17.9 | |
| efalizumab (Raptiva®) | 25/10/2005 | 24/08/2006 | 43.3 | |
| treprostinil sodium (Remodulin®) | 24/02/2006 | 20/07/2006 | 20.9 | |
| triptorelin pamoate (Trelstar®) | 27/02/2006 | 20/07/2006 | 20.4 | |
| trospium chloride (Trosec®) | 24/03/2006 | 24/08/2006 | 21.9 | |
| emtricitabine / tenofovir disoproxil fumarate (Truvada®) | 29/05/2006 | 25/10/2006 | 21.3 | |
| voriconazole (Vfend® – candidemia) | 24/03/2006 | 25/10/2006 | 30.7 | |
| tenofovir disoproxil fumarate (Viread®) | 11/08/2005 | 15/03/2006 | 30.9 | |
| Median | 21.9 | 6.4 | ||
| ramipril / hydrochlorothiazide (Altace HCT®) | 26/03/2007 | 14/06/2007 | 11.4 | |
| entecavir (Baraclude®) | 12/12/2006 | 28/11/2007 | 50.1 | |
| varenicline tartrate (Champix®) | 21/03/2007 | 16/08/2007 | 21.1 | |
| ciprofloxacin hydrochloride & dexamethasone otic suspension (Ciprodex®) | 15/06/2007 | 18/10/2007 | 17.9 | |
| deferasirox (Exjade®) | 26/10/2006 | 19/04/2007 | 25.0 | |
| adalimumab (Humira® – ankylosing spondylitis) | 12/07/2007 | 19/12/2007 | 22.9 | |
| adalimumab (Humira® – crohn's disease) | 12/07/2007 | 19/12/2007 | 22.9 | |
| adefovir dipivoxil (Hepsera®) | 29/06/2007 | 18/10/2007 | 15.9 | |
| alglucosidase (Myozyme®) | 10/10/2006 | 14/06/2007 | 35.3 | |
| abatacept (Orencia®) | 26/10/2006 | 27/06/2007 | 34.9 | |
| darunavir (Prezista®) | 29/08/2006 | 14/02/2007 | 24.1 | |
| sildenafil citrate (Revatio®) | 20/09/2006 | 14/02/2007 | 21.0 | |
| rituximab (Rituxan®) | 26/06/2006 | 14/02/2007 | 33.3 | |
| lanreotide acetate (Somatuline Autogel®) | 20/02/2007 | 19/07/2007 | 21.3 | |
| sunitinib malate (Sutent®) | 20/07/2006 | 28/03/2007 | 35.9 | |
| Median | 24.1 | 10.0 |
*
Based on drugs with a recommendation of “List,” “List with criteria/conditions” and “list in a similar manner to other drugs in class” issued between January 1, 2005 and May 1, 2008.