Table 5.
Effects of specific clusters of MetS components on central arterial structure and function: women
| C | T–B–W | H–B–W | G–B–W | G–T–B(–W) | G–H–B(–W) | P-value& | |
|---|---|---|---|---|---|---|---|
| 3344 | 45 | 34 | 62 | 13 | 20 | ||
| APWV (cm/s) | 648 ± 208 | 895 ± 240 | 849 ± 203 | 1053 ± 383 | 1064 ± 325 | 951 ± 225 | 0.01 |
| APWV/MBP (cm/s) | 718 ± 192 | 840 ± 219 | 793 ± 194 | 975 ± 380 | 953 ± 262 | 990 ± 230 | 0.05 |
| CCA diameter (mm) | 5.2 ± 0.6 | 5.7 ± 0.7 | 5.6 ± 0.5 | 5.9 ± 0.8 | 5.8 ± 0.9 | 5.8 ± 0.6 | 0.36 |
| CCA IMT (mm) | 0.53 ± 0.10 | 0.62 ± 0.11 | 0.62 ± 0.15 | 0.65 ± 0.13 | 0.59 ± 0.09 | 0.66 ± 0.12 | 0.35 |
| CCA W/L | 20.7 ± 3.4 | 22.1 ± 4.1 | 21.9 ± 4.3 | 22.3 ± 4.3 | 20.7 ± 4.3 | 22.7 ± 3.4 | 0.72 |
| CCA CSA | 19.5 ± 5.3 | 25.1 ± 6.5 | 24.8 ± 8.2 | 27.4 ± 7.8 | 23.9 ± 5.6 | 27.0 ± 7.8 | 0.28 |
| CCA circum. stress | 18.9 ± 4.3 | 23.4 ± 3.9 | 23.6 ± 5.1 | 24.4 ± 5.7 | 23.0 ± 5.0 | 22.0 ± 4.3 | 0.41 |
| CCA distensibility (µm/mm/mmHg) | 224 ± 105 | 132 ± 52 | 132 ± 64 | 125 ± 57 | 138 ± 72 | 154 ± 62 | 0.44 |
| CCA strain (%) | 9.8 ± 3.8 | 7.3 ± 2.9 | 6.7 ± 2.7 | 7.6 ± 2.5 | 8.1 ± 4.7 | 7.6 ± 2.5 | 0.53 |
| CCA stiffness | 5.87 ± 3.45 | 8.08 ± 4.31 | 8.38 ± 4.7 | 8.08 ± 3.26 | 7.09 ± 2.35 | 7.62 ± 4.34 | 0.87 |
| CCA plaque, % (n) | 2.9 (97) | 11.1 (5) | 0 | 16.1 (10) | 0 | 20.0 (4) | 0.06 |
| CCA calcification, % (n) | 0.9 (30) | 6.5 (3) | 0 | 11.2 (7) | 0 | 10.0 (2) | 0.23 |
| CCA stenosis, % (n) | 0.7 (23) | 2.2 (1) | 0 | 6.5 (4) | 0 | 0 | 0.30 |
| CCA flow (mL/min) | 1230 ± 261 | 1092 ± 273 | 1125 ± 310 | 1131 ± 340 | 1044 ± 228 | 1066 ± 219 | 0.82 |
| Prevalent CVD, % (n) | 0.8 (27) | 2.2 (1) | 0 | 6.5 (4) | 7.6 (1) | 15.0 (3) | 0.28 |
| Prevalent diabetes, % (n) | 2.2 (74) | 2.2 (1) | 2.9 (1) | 66.1 (41) | 76.9 (10) | 75.0 (15) | 0.0001 |
C, control; G, elevated glucose component; H, low HDL cholesterol component; T, elevated triglycerides component; B, elevated blood pressure component; W, abdominal obesity.
&ANOVA excluding those without the MetS.