Figure 3.

The age effect on the cost and efficiency of the cortical networks. A, Plots of the T statistic of the age effect on the network cost, local efficiency, and global efficiency as a function of the sparsity. Significant positive age effect on the cost was found over the entire sparsity. Local efficiency but not global efficiency showed significant age effect over the majority of the sparsity range. In accordance, significant age effect was observed on both the integrated network cost (B) and integrated local efficiency (C), but the integrated global efficiency showed no significant age effect (D). Notably, all results here were calculated after adjusting for the effects of brain size and sex, using a general linear model.