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. Author manuscript; available in PMC: 2010 Mar 3.
Published in final edited form as: Cancer Res. 2008 Sep 1;68(17):7015–7024. doi: 10.1158/0008-5472.CAN-08-0814

Figure 1. Increased HEXIM1 expression inhibits estrogen-regulated mammary gland morphogenesis due to changes in proliferation and apoptosis.

Figure 1

A. MMTV/HEXIM1 mice were treated as described in Materials and Methods. Representative whole mounts were obtained from MMTV and MMTV/HEXIM1 mice with Carmine alum stain. Original magnification is X40 for all panels.

B. BrdU-labeled nuclei were detected by immunostaining and apoptotic nuclei were stained by TUNEL. Quantitation of positively-labeled MMEC nuclei from at least 1000 nuclei each from 5 mice per group (−/+DOX) is shown. Original magnification is X40 for all panels.