Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2010 Feb 12;10:1. doi: 10.1186/1471-5945-10-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright ©2010 Suárez-Fariñas et al; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

PMC Copyright notice

Histological classification of response. Clinical photographs, haematoxylin and eosin (H&E) and keratin 16 staining of non-lesional skin, and lesional skin pre and post alefacept treatment in (A) a responding patient and (B) a non-responding patient. Lesional skin in both patients demonstrated characteristic features of psoriasis: epidermal acanthosis, parakeratosis, loss of the granular layer, elongation of the rete, dilated blood vessels, and a dense inflammatory infiltrate in the dermis. There was strong K16 staining. Only the responding patient showed resolution of inflammation and K16 staining to non-lesional appearance.