Table 1.
Baseline characteristics at enrollment of study children by study site
| Site | Mut | Yao | Gar | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Drug Groups | SPAQ | SP | AQ | SPAQ | SP | AQ | SPAQ | SP | AQ |
| Age (mean in months ± SD) | 29 ± 15.5 | 27 ± 14.8 | 27 ± 15.2 | 29.4 ± 14.5 | 30 ± 15.1 | 29 ± 13.8 | 27 ± 15.4 | 26.6 ± 16.5 | 27.4 ± 17.2 |
| Female/Male ratio | 1 | 0.9 | 1 | 0.7 | 1.2 | 0.82 | 0.74 | 0.82 | 1.2 |
| Weight (kg) (mean ± SD) | 12.5 ± 3.5 | 12.2 ± 3.2 | 12.2 ± 4.1 | 13.02 ± 3.0 | 12.6 ± 3.4 | 12.9 ± 3.2 | 10.84 ± 3.3 | 10.86 ± 2.7 | 10.59 ± 3.3 |
| Geo mean parasitemia (± SD) | 39601 (± 48160) |
27014 (± 49560) |
22072 (± 30260) |
7776 (± 27120) |
6721 (± 25200) |
5364 (± 25720) |
7264 (± 27730) |
5668 (± 19040) |
6294 (± 26890) |
| Temp °C (mean ± SD) | 38.9 ± 1.1 | 38.7 ± 1.1 | 38.7 ± 1.0 | 38.2 ± 1.2 | 38.3 ± 1.0 | 38.4 ± 1.2 | 37.9 ± 0.6 | 38.0 ± 0.6 | 37.7 ± 0.7 |
A, B, C, were groups to which independently at each site drugs were randomly assigned. SP- Sulphadoxine-pyrimethamine, AQ - Amodiaquine, SPAQ- combination of AQ and SP, SD- Standard Deviation. Ecotypes; Mutengene (Mut) is in the littoral-forest, Yaoundé (Yao) is in the forest-savannah mosaic and Garoua (Gar) is in the guinnea-savannah