Table 2.
Characteristic | Quartile 1 (0.7–1.4 μg/dL) | Quartile 2 (1.5–2.3 μg/dL) | Quartile 3 (2.4–3.7 μg/dL) | Quartile 4 (3.8–52.9 μg/dL) | p-Value for trend |
---|---|---|---|---|---|
Median BLL (μg/dL) | 0.70 | 1.90 | 3.00 | 5.00 | |
ALAD2 carriers, 1-2/2-2 (%) | 15.1 | 14.2 | 11.6 | 13.5 | |
BP (mmHg) | |||||
Systolic BP | 113.5 ± 0.41 | 116.9 ± 0.46 | 121.1 ± 0.81 | 124.6 ± 0.58 | < 0.001 |
Diastolic BP | 71.6 ± 0.45 | 73.0 ± 0.42 | 74.3 ± 0.44 | 75.3 ± 0.50 | < 0.001 |
Systolic BP = 140 mmHg (%)a | 3.0 | 7.2 | 11.9 | 15.1 | < 0.001 |
Diastolic BP = 90 mmHg (%)a | 3.2 | 4.6 | 6.2 | 8.0 | < 0.001 |
Hypertension, yes (%)b | 10.9 | 18.4 | 27.4 | 33.1 | < 0.001 |
Race (%) | |||||
Non-Hispanic white | 83.7 | 83.5 | 81.8 | 77.6 | |
Non-Hispanic black | 10.8 | 11.4 | 12.1 | 15.4 | < 0.01 |
Mexican American | 5.6 | 5.1 | 6.1 | 7.0 | |
Age [years (%)] | |||||
17–39 | 71.3 | 50.6 | 39.7 | 28.9 | |
40–59 | 21.6 | 32.6 | 32.8 | 35.5 | < 0.001 |
≥ 60 | 7.1 | 16.9 | 27.5 | 35.6 | |
Sex (%) | |||||
Male | 26.6 | 40.2 | 53.8 | 69.1 | < 0.001 |
Female | 73.4 | 59.8 | 46.2 | 30.9 | |
BMI (kg/m2) | 26.66 ± 0.47 | 26.70 ± 0.21 | 26.70 ± 0.21 | 26.63 ± 0.22 | 0.9 |
Smoking history (%) | |||||
Current | 14.2 | 21.7 | 29.8 | 36.6 | |
Former | 19.16 | 25.4 | 23.9 | 32.1 | < 0.001 |
Never | 66.7 | 52.9 | 46.3 | 31.3 | |
Alcohol use (%) | |||||
None | 52.5 | 50.8 | 46.0 | 40.6 | |
< 4 drinks/week | 31.6 | 28.4 | 27.2 | 24.3 | < 0.001 |
≥ 4 drinks/week | 15.9 | 20.9 | 26.8 | 35.2 | |
Education (%) | |||||
< High school | 16.6 | 15.6 | 25.7 | 32.2 | |
Completed high school | 36.7 | 33.1 | 34.2 | 34.7 | < 0.001 |
Some college | 46.7 | 51.2 | 40.2 | 33.1 | |
Serum creatinine (mg/dL) | 0.78 ± 0.01 | 0.83 ± 0.01 | 0.88 ± 0.01 | 0.94 ± 0.01 | < 0.001 |
Serum calcium (mg/dL) | 9.15 ± 0.03 | 9.17 ± 0.03 | 9.22 ± 0.03 | 9.21 ± 0.04 | 0.02 |
Log glycosylated hemoglobin (%) | 1.64 ± 0.01 | 1.67 ± 0.01 | 1.70 ± 0.01 | 1.70 ± 0.01 | < 0.001 |
Hematocrit (%) | 40.72 ± 0.24 | 41.72 ± 0.14 | 42.83 ± 0.20 | 43.19 ± 0.16 | < 0.001 |
Values are percent or mean ± SE.
Subject with systolic BP of ≥ 140 mmHg or diastolic BP of ≥ 90 mmHg not currently treated for hypertension.
Hypertension defined as a self-report of currently taking antihypertensive medication, systolic BP of ≥ 140 mmHg, or diastolic BP of ≥ 90 mmHg.