Table 5.

Lipid-adjusted serum concentration (ng/g) and prevalent prostate cancer in 1999–2004 NHANES adult participants, by tertile.

	Not detectable		Detectable
Chemical	< LOD	< 33rd	33rd –67th	> 67th	ptrend
β-HCH
Median concentration	—	6.2	16.2	53.9
Cases/no.	5/453	9/528	23/531	21/307
Age-adjusted OR (95% CI)	1.0	1.0	1.44 (0.55–3.78)	3.10 (1.36–7.11)	0.007
Adjusted OR (95% CI)a	1.0	1.0	1.46 (0.52–4.13)	3.36 (1.24–9.10)	0.02
p,p ′-DDE
Median concentration	—	113.0	386.0	1530.0
Cases/no.	0/3	8/599	28/692	23/547
Age-adjusted OR (95% CI)	1.0	1.0	1.89 (0.71–5.04)	2.02 (0.76–5.32)	0.16
Adjusted OR (95% CI)a	1.0	1.0	2.05 (0.76–5.50)	2.64 (0.92–7.57)	0.07
Oxychlordane
Median concentration	—	8.0	17.2	37.0
Cases/no.	0/273	5/488	19/506	29/441
Age-adjusted OR (95% CI)	1.0	1.0	3.38 (1.02–11.3)	3.39 (1.03–11.1)	0.04
Adjusted OR (95% CI)a	1.0	1.0	3.54 (0.91–13.8)	3.54 (0.92–13.6)	0.06
Trans-nonachlor
Median concentration	—	9.9	24.8	56.4
Cases/no.	0/154	3/521	12/571	41/582
Age-adjusted OR (95% CI)	1.0	1.0	4.76 (1.13–20.1)	9.51 (2.22–40.8)	0.002
Adjusted OR (95% CIa	1.0	1.0	5.84 (1.06–32.2)	14.1 (2.55–77.9)	0.002
Heptachlor epoxide
Median concentration	—	5.0	8.9	18.0
Cases/no.	10/681	7/339	12/360	21/311
Age-adjusted OR (95% CI)	1.0	0.68 (0.20–2.29)	1.39 (0.57–3.34)	1.79 (0.59–5.47)	0.15
Adjusted OR (95% CI)a	1.0	1.01 (0.31–3.20)	1.65 (0.73–3.76)	1.91 (0.70–5.33)	0.12
Dieldrin
Median concentration	—	4.8	7.9	14.7
Cases/no.	0/257	6/286	6/362	25/343
Age-adjusted OR (95% CI)	1.0	1.0	0.98 (0.31–3.08)	2.69 (1.09–6.68)	0.03
Adjusted OR (95% CI)a	1.0	1.0	1.06 (0.30–3.73)	2.74 (1.01–7.49)	0.04

^aAdjusted for age, race, and ethnicity, BMI, education, smoking, data cycle, and marital status.