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. 2009 Aug 31;118(1):73–79. doi: 10.1289/ehp.0901149

Figure 3.

Figure 3

DNA synthesis and retention of radiolabeled DNA in differentiating PC12 cells. In (A) cells were exposed to test agents simultaneously with NGF for 2 days, and then [3H]thymidine incorporation into DNA was measured for a 1-hr period at the end of exposure. In (B), undifferentiated cells were radiolabeled with [3H]thymidine; cells were then exposed simultaneously to test agents with NGF for 6 days, and the radiolabel retained in the DNA fraction was determined. (C) Retained radiolabel after 6 days relative to the DNA content. Data represent mean ± SE obtained from the number of determinations shown in parentheses. For AC, ANOVA: treatment, p < 0.0001.

*p < 0.05 compared with the corresponding control group.