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. 2010 Mar 4;5(3):e9536. doi: 10.1371/journal.pone.0009536

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Lee et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A and B) Standard curve generated by quantifying intensity of known concentrations of NP-chitosan-Cy5.5 or NP-CTX-chitosan-Cy5.5. (C and D) Measured fluorescence intensity of nanoparticles in serum. Each data point represents the mean fluorescence intensity integrated above the baseline. This baseline subtraction avoids systematic errors from underlying autofluorescence. Error bars represent standard errors of the mean. The curve indicates an exponential decay curve fit to the data (n = 3 mice per time point).