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. 2010 Mar 4;5(3):e9536. doi: 10.1371/journal.pone.0009536

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Lee et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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Relative fluorescence intensity was determined using the Odyssey scanner. Bars represent tissue from animals that were not injected with nanoparticles (blue), or injected with nanoparticles and harvested 6 hours (red), 24 hours (green), or 48 hours (purple) after injection. Bars represent the average of 3 animals for each nanoparticle at each time point. The error bars are standard deviation from the mean. (A) Ex vivo biodistribution of NP-chitosan-Cy5.5 non-targeted nanoparticle. (B) Ex vivo biodistribution of NP-CTX-chitosan-Cy5.5 targeted nanoparticle.