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. 2010 Mar;176(3):1122–1129. doi: 10.2353/ajpath.2010.090733

Figure 2.

Figure 2

Chy mice, but not K14-VEGFR-3-Ig mice, have increased dermal collagen content. A: Tail cross sections taken 5 mm from the tail tip and stained with Van Gieson (pink = collagen; red = tendon, bone; yellow = keratin, muscle) display an increased dermal matrix in Chy (top), but not in K14-VEGFR-3-Ig (bottom) mice as compared with their respective wild-type controls. Scale bar = 200 μm. B: Quantification of dermal collagen content by hydroxyproline determination verifies the increased collagen density in the Chy mouse (*P = 0.02) but not the K14-VEGFR-3-Ig mouse as compared with their littermates (“WT”).