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. 2010 Mar;176(3):1494–1504. doi: 10.2353/ajpath.2010.090655

Figure 6.

Figure 6

The proteolytic activity of ADAMTS9 is required for its anti-angiogenic effect. A: Two representative fields each show the effect of overexpressing the vector alone, ADAMTS1, ADAMTS9, or ADAMTS9 (E435Q) in HBMECs. B: Quantitative analysis illustrates a statistically significant reduction in tube-like structures following expression of ADAMTS1 and ADAMTS9, but not ADAMTS9 E435Q. *P < 0.05.