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. Author manuscript; available in PMC: 2010 Mar 4.
Published in final edited form as: Acta Neuropathol. 2008 Jul 19;117(4):369–384. doi: 10.1007/s00401-008-0410-2

Table 1.

Demographics of the subjects included in this study

Case Diagnosis Sex/
race
Age
(years)
Brain weight
(kg)
PMIa
(h)
Strg timeb
(months)
Cause of deathc
Normal comparison subjects
 568 Comparison subject F/W 60 1.345 9.5 61.4 ASCVD
 634 Comparison subject M/W 52 1.620 16.2 51.9 ASCVD
 686 Comparison subject F/W 52 1.240 22.6 44.7 ASCVD
 700 Comparison subject M/W 42 1.670 26.1 45.0 ASCVD
 794 Comparison subject M/B 52 1.255 20.0 26.6 Cardiomyopathy
 795 Comparison subject M/W 68 1.400 12.0 25.5 Ruptured abdominal
 aortic aneurysm
 871 Comparison subject M/W 28 1.440 16.5 13.0 Trauma
 Mean 50.6 1.424 17.6 38.3
 CV* 0.25 0.12 0.33 0.45
Subjects with schizophrenia
 466 Chronic undifferentiated schizophrenia M/B 48 1.270 19.0 81.0 ASCVD
 640 Chronic paranoid schizophrenia M/W 49 1.260 5.2 49.2 Pulmonary embolism
 656 Schizoaffective disorderd F/B 47 1.350 20.1 48.1 Suicide by gun shot
 829 Schizoaffective disorderd,i,j M/W 25 1.160 5.0 17.6 Suicide by drug overdose
 843 Chronic disorganized schizophrenia F/W 41 1.490 17.1 16.6 Suicide by jumping
 878 Disorganized schizophreniad M/W 33 1.385 10.8 10.5 Myocardial fibrosis
 900 Chronic paranoid schizophrenia M/B 56 1.570 12.3 12.0 ASCVD
 904 Schizoaffective disorder M/W 33 1.565 29.0 7.1 Bronchopneumonia
 917 Chronic undifferentiated schizophrenia F/W 71 1.150 23.8 7.4 ASCVD
 Mean 44.8 1.356 15.8 27.7
 CV* 0.31 0.12 0.52 0.93
Subjects with mood disorders
 203 Bipolar disorder with psychotic featuresf,k F/W 70 1.370 19.3 132.3 ASCVD
 505 Major depressiond M/W 57 1.440 12.8 68.6 Suicide by gun shot
 564 Major depression with psychotic features F/W 56 1.355 16.6 60.5 Suicide by hanging
 602 Major depressiond M/W 56 1.375 11.8 54.8 Suicide by gun shot
 652 Dysthymia, alcohol induced mood disorderd M/W 44 1.385 21.9 48.9 Pneumonia
 697 Bipolar disorder with psychotic featuresk M/W 39 1.530 25.9 44.3 Suicide by exsanguinations
 699 Major depression M/W 65 1.435 5.5 42.7 Suicide by gunshot
 735 Major depressione,i F/W 40 1.385 14.0 36.7 Pulmonary thromboembolism
 803 Major depression F/W 65 1.265 18.0 25.6 Trauma
 816 Major depression with psychotic featuresk F/W 55 1.430 13.0 23.2 Myocardial fibrosis
 834 Alcohol induced mood disorderd M/W 50 1.350 9.5 22.9 Pneumonia
 862 Major depressiond,g M/W 49 1.520 10.0 17.3 Upper GI bleed
 868 Major depressiond,h M/W 47 1.530 10.5 16.7 Trauma
 Mean 53.3 1.413 14.5 45.7
 CV* 0.18 0.06 0.39 0.68
*

Coefficient of variation CV = SD/mean

a

PMI, postmortem interval in hours

b

Storage time, tissue storage time at −30°C in months

c

ASCVD, atherosclerotic coronary vascular disease

d

Alcohol dependence, current at time of death

e

Alcohol dependence, in remission at time of death

f

Alcohol abuse, in remission at time of death

g

Other substance dependence, in remission at time of death

h

Other substance abuse, current at time of death

i

Other substance abuse, in remission at time of death

j

Schizophrenic subject off medications at time of death

k

Psychiatric subjects with history of treatment with antipsychotic medications

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