Table 1.
Demographics of the subjects included in this study
Case | Diagnosis | Sex/ race |
Age (years) |
Brain weight (kg) |
PMIa (h) |
Strg timeb (months) |
Cause of deathc |
---|---|---|---|---|---|---|---|
Normal comparison subjects | |||||||
568 | Comparison subject | F/W | 60 | 1.345 | 9.5 | 61.4 | ASCVD |
634 | Comparison subject | M/W | 52 | 1.620 | 16.2 | 51.9 | ASCVD |
686 | Comparison subject | F/W | 52 | 1.240 | 22.6 | 44.7 | ASCVD |
700 | Comparison subject | M/W | 42 | 1.670 | 26.1 | 45.0 | ASCVD |
794 | Comparison subject | M/B | 52 | 1.255 | 20.0 | 26.6 | Cardiomyopathy |
795 | Comparison subject | M/W | 68 | 1.400 | 12.0 | 25.5 | Ruptured abdominal aortic aneurysm |
871 | Comparison subject | M/W | 28 | 1.440 | 16.5 | 13.0 | Trauma |
Mean | 50.6 | 1.424 | 17.6 | 38.3 | |||
CV* | 0.25 | 0.12 | 0.33 | 0.45 | |||
Subjects with schizophrenia | |||||||
466 | Chronic undifferentiated schizophrenia | M/B | 48 | 1.270 | 19.0 | 81.0 | ASCVD |
640 | Chronic paranoid schizophrenia | M/W | 49 | 1.260 | 5.2 | 49.2 | Pulmonary embolism |
656 | Schizoaffective disorderd | F/B | 47 | 1.350 | 20.1 | 48.1 | Suicide by gun shot |
829 | Schizoaffective disorderd,i,j | M/W | 25 | 1.160 | 5.0 | 17.6 | Suicide by drug overdose |
843 | Chronic disorganized schizophrenia | F/W | 41 | 1.490 | 17.1 | 16.6 | Suicide by jumping |
878 | Disorganized schizophreniad | M/W | 33 | 1.385 | 10.8 | 10.5 | Myocardial fibrosis |
900 | Chronic paranoid schizophrenia | M/B | 56 | 1.570 | 12.3 | 12.0 | ASCVD |
904 | Schizoaffective disorder | M/W | 33 | 1.565 | 29.0 | 7.1 | Bronchopneumonia |
917 | Chronic undifferentiated schizophrenia | F/W | 71 | 1.150 | 23.8 | 7.4 | ASCVD |
Mean | 44.8 | 1.356 | 15.8 | 27.7 | |||
CV* | 0.31 | 0.12 | 0.52 | 0.93 | |||
Subjects with mood disorders | |||||||
203 | Bipolar disorder with psychotic featuresf,k | F/W | 70 | 1.370 | 19.3 | 132.3 | ASCVD |
505 | Major depressiond | M/W | 57 | 1.440 | 12.8 | 68.6 | Suicide by gun shot |
564 | Major depression with psychotic features | F/W | 56 | 1.355 | 16.6 | 60.5 | Suicide by hanging |
602 | Major depressiond | M/W | 56 | 1.375 | 11.8 | 54.8 | Suicide by gun shot |
652 | Dysthymia, alcohol induced mood disorderd | M/W | 44 | 1.385 | 21.9 | 48.9 | Pneumonia |
697 | Bipolar disorder with psychotic featuresk | M/W | 39 | 1.530 | 25.9 | 44.3 | Suicide by exsanguinations |
699 | Major depression | M/W | 65 | 1.435 | 5.5 | 42.7 | Suicide by gunshot |
735 | Major depressione,i | F/W | 40 | 1.385 | 14.0 | 36.7 | Pulmonary thromboembolism |
803 | Major depression | F/W | 65 | 1.265 | 18.0 | 25.6 | Trauma |
816 | Major depression with psychotic featuresk | F/W | 55 | 1.430 | 13.0 | 23.2 | Myocardial fibrosis |
834 | Alcohol induced mood disorderd | M/W | 50 | 1.350 | 9.5 | 22.9 | Pneumonia |
862 | Major depressiond,g | M/W | 49 | 1.520 | 10.0 | 17.3 | Upper GI bleed |
868 | Major depressiond,h | M/W | 47 | 1.530 | 10.5 | 16.7 | Trauma |
Mean | 53.3 | 1.413 | 14.5 | 45.7 | |||
CV* | 0.18 | 0.06 | 0.39 | 0.68 |
Coefficient of variation CV = SD/mean
PMI, postmortem interval in hours
Storage time, tissue storage time at −30°C in months
ASCVD, atherosclerotic coronary vascular disease
Alcohol dependence, current at time of death
Alcohol dependence, in remission at time of death
Alcohol abuse, in remission at time of death
Other substance dependence, in remission at time of death
Other substance abuse, current at time of death
Other substance abuse, in remission at time of death
Schizophrenic subject off medications at time of death
Psychiatric subjects with history of treatment with antipsychotic medications