. Author manuscript; available in PMC: 2010 Aug 1.

Published in final edited form as: Dev Biol. 2009 May 9;332(1):104–115. doi: 10.1016/j.ydbio.2009.05.541

Table 1.

Mutation of Rb and E2f4 leads to embryonic lethality between E10.5 and E13.5.

	Total #	Rb^−/−;E2f4^+/+	Rb^−/−;E2f4^+/−	Rb^−/−;E2f4^−/−
Age	Embryos	obs (lv) exp	obs (lv) exp	obs (lv) exp
E13.5	201	14 (11) 13	26 (24) 25	4 (3) 13
E11.5	366	18 (15) 23	49 (46) 46	26 (14) 23
E10.5	386	27 (24) 24	53 (43) 48	19 (13) 24
E9.5	103	2 (2) 6	15 (13) 13	9 (7) 6

Frequency of embryos arising from Rb^+/−;E2f4^+/− intercrosses. Only embryos homozygous for the Rb mutation are shown. Obs=observed number, lv=live (as judged by heartbeat or morphology), exp=expected number.