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. Author manuscript; available in PMC: 2010 Mar 4.
Published in final edited form as: Biometrika. 2007 Mar 1;94(1):185–198. doi: 10.1093/biomet/asm010

Table 1.

Simulation study. Point estimates for β1, with true value 1, together with the coefficients of determination (R2) and the 95% confidence intervals based on the empirical likelihood (EL) and normal approximation (Norm) methods. Also displayed are the averages of the lower and upper endpoints of the confidence intervals, their average midpoints, their average lengths, and the associated coverage probabilities for the simulated data (a) when X and Z are independent, and (b) when X and Z are strongly correlated.

Estimate R2 Confidence Interval Midpoint Length Coverage
n Case Naive ME Naive X observed EL Norm EL Norm EL Norm EL Norm

(a) X and Z are independent

100 1 0.649 1.027 0.464 0.525 (0.511, 1.624) (0.438, 1.615) 1.072 1.027 1.114 1.177 93.7 94.3
2 0.643 1.021 0.467 0.525 (0.500, 1.627) (0.438, 1.605) 0.969 1.021 1.126 1.167 94.0 94.7
3 0.655 1.042 0.861 0.915 (0.806, 1.318) (0.740, 1.324) 1.082 1.042 0.522 0.544 95.7 92.7
4 0.657 1.048 0.473 0.532 (0.505, 1.676) (0.364, 1.733) 1.090 1.048 1.171 1.369 96.3 94.3

500 1 0.665 1.007 0.446 0.502 (0.793, 1.221) (0.793, 1.221) 0.981 1.007 0.427 0.428 94.7 94.8
2 0.658 0.997 0.445 0.501 (0.786, 1.217) (0.777, 1.218) 1.006 0.997 0.432 0.441 95.8 94.5
3 0.660 1.000 0.858 0.917 (0.913, 1.071) (0.916, 1.083) 1.007 1.000 0.158 0.167 93.7 95.8
4 0.663 1.003 0.446 0.502 (0.788, 1.144) (0.785, 1.221) 0.990 1.003 0.363 0.436 94.8 94.9

(b) X and Z are strongly correlated

100 1 0.569 1.082 0.65 0.688 (0.306, 2.016) (-0.001, 2.165) 1.061 1.082 1.71 2.166 92.7 97.0
2 0.589 1.094 0.641 0.677 (0.357, 1.916) (0.256, 1.931) 0.971 1.094 1.569 1.675 96.3 95.0
3 0.568 1.088 0.879 0.922 (0.530, 1.907) (0.044, 2.132) 1.019 1.088 1.377 2.088 94.6 96.7
4 0.564 0.983 0.645 0.674 (0.261, 2.082) (-0.296, 2.445) 1.172 0.983 1.821 2.741 94.7 97.7

500 1 0.586 1.013 0.631 0.665 (0.725, 1.227) (0.720, 1.306) 1.026 1.013 0.522 0.586 94.8 94.2
2 0.582 1.005 0.631 0.664 (0.716, 1.221) (0.715, 1.296) 0.981 1.005 0.544 0.581 95.6 94.5
3 0.582 0.991 0.912 0.942 (0.897, 1.062) (0.892, 1.125) 0.993 0.991 0.168 0.233 98.6 95.3
4 0.586 1.011 0.630 0.664 (0.728, 1.228) (0.727, 1.295) 1.023 1.011 0.510 0.568 96.4 94.6