TABLE 3.
Comparison by laboratory test site of MICs for six antimicrobial agents incubated in ambient air and CO2 atmospheric conditions for 39 Brucella isolatesa
| Antimicrobial agent | Incubation condition | Test site | No. of occurrences at indicated MIC (μg/ml) |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.03 | 0.06 | 0.12 | 0.25 | 0.5 | 1 | 2 | 4 | 8 | 16 | |||
| Doxycycline | AA | A | 3 | 26 | 2 | |||||||
| B | 13 | 20 | 2 | |||||||||
| C | 9 | 23 | 2 | |||||||||
| CO2 | A | 26 | 11 | 2 | ||||||||
| B | 18 | 13 | 4 | 3 | 1 | |||||||
| D | 3 | 17 | 10 | 7 | 1 | 1 | ||||||
| Gentamicin | AA | A | 1 | 16 | 14 | |||||||
| B | 21 | 14 | ||||||||||
| C | 1 | 19 | 15 | |||||||||
| CO2 | A | 1 | 2 | 19 | 16 | 1 | ||||||
| B | 1 | 23 | 15 | |||||||||
| D | 1 | 3 | 22 | 13 | ||||||||
| Rifampin | AA | A | 1 | 3 | 19 | 7 | ||||||
| B | 3 | 21 | 11 | |||||||||
| C | 1 | 9 | 16 | 9 | ||||||||
| CO2 | A | 6 | 32 | 1 | ||||||||
| B | 1 | 5 | 19 | 14 | ||||||||
| D | 1 | 6 | 15 | 16 | 1b | |||||||
| Streptomycin | AA | A | 1 | 12 | 18 | |||||||
| B | 9 | 24 | 2 | |||||||||
| C | 6 | 25 | 4 | |||||||||
| CO2 | A | 14 | 15 | 10 | ||||||||
| B | 3 | 35 | 1 | |||||||||
| D | 1 | 18 | 16 | 4 | ||||||||
| Tetracycline | AA | A | 8 | 22 | 1 | |||||||
| B | 1 | 24 | 10 | |||||||||
| C | 8 | 27 | ||||||||||
| CO2 | A | 28 | 11 | |||||||||
| B | 21 | 13 | 5 | |||||||||
| D | 1 | 3 | 17 | 16 | 2 | |||||||
| Trimethoprim-sulfamethoxazolec | AA | A | 3 | 24 | 4 | |||||||
| B | 18 | 17 | ||||||||||
| C | 2 | 17 | 16 | |||||||||
| CO2 | A | 9 | 27 | 3 | ||||||||
| B | 1 | 15 | 18 | 5 | ||||||||
| D | 4 | 24 | 9 | 2 | ||||||||
a
For site A, ambient air (AA) data were available for only 31 isolates (30 for rifampin), while each of the other 2 AA testing sites had 35 AA results (4/39 isolates required CO2); site C had 34 AA results available for doxycycline.
b
One rifampin MIC was ≥16 μg/ml.
c
Only the trimethoprim portion of the 1/19 drug ratio is displayed for the MIC.