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. Author manuscript; available in PMC: 2010 Sep 1.
Published in final edited form as: Aging Cell. 2009 Jul 9;8(5):542–552. doi: 10.1111/j.1474-9726.2009.00504.x

Figure 3. S6K modulates heart aging by regulating DILP2 levels.

Figure 3

A) Decreased dilp2 mRNA levels in the S6K mutant and by IPC expression of dnS6K. (p<0.05, unpaired, two-tailed t-test, n=3). Decreased dilp2 expression levels with dnS6K expression are shown fold change relative to control. B) Expression of dnS6K in the IPCs leads to increased glucose levels (p<0.001, unpaired, two-tailed t-test, n=8) compared to control. Glucose levels are shown fold change compared to control. These experiments have been performed 2 times independently. C, D) Expression of dnS6K in the IPCs does not lead to a change in the number of IPCs. Anterior is on the left and posterior on the right. The 2 sets of the IPC clusters are marked by circles and the IPCs by small arrows (7 per cluster). (C) Control genotype: (dilp2-Gal4) yw; dilp2-Gal4, UAS-GFP/+. (D) Experimental genotype: (dilp2-Gal4; UAS-dnS6K) yw; dilp2-Gal4, UAS-GFP/+; UAS-dnS6K/+. Images at 400X and Bar is 0.1 mm.