TABLE 3.
Metabolome analysis to determine the change in in vivo metabolite concentrations after decoyinine addition
| Compound | In vivo concn (mM) without decoyinine additiona | In vivo concn (mM) with decoyinine additiona |
|---|---|---|
| Glucose-6-phosphate | 6.3 | 7.7 |
| Fructose-6-phosphate | 2.8 | 3.6 |
| Fructose-1,6-bisphosphate | 4.5 | 0.8 |
| Dihydroxyacetone phosphate | 0.5 | 0.2 |
| Glyceraldehyde 3-phosphate | 46 | 36 |
| Phosphoenolpyruvate | 22 | 20 |
| Lactate | 270 | 410 |
| Acetyl-CoA | 7.7 | 7.3 |
| Citrate | 1.7 | 7.1 |
| Isocitrate | 0.3 | 0.4 |
| 2-Oxoglutarate | 0.5 | 1.4 |
| Succinate | 54 | 38 |
| Fumarate | 4.3 | 4.2 |
| Malate | 1.7 | 2.6 |
| Ala | 150 | 190 |
| Val | 9.9 | 40 |
| Homoserine | 3.9 | 3.7 |
| Thr | 21 | 44 |
| Ile | 17 | 35 |
| Leu | 11 | 31 |
| Asn | 0.8 | 1.4 |
| Asp | 25 | 200 |
| Lys | 12 | 21 |
| GTP | 0.4 | 0.19 |
| ATP | 3.1 | 6.6 |
| ppGpp | NDb | ND |
a
The standard deviations of the values were less than 20%.
b
ND, not determined.