Skip to main content
. Author manuscript; available in PMC: 2010 Mar 4.
Published in final edited form as: J Biol Chem. 2002 Feb 8;277(16):13804–13811. doi: 10.1074/jbc.M112039200

FIG. 4. Contribution of ADH1 and/or ADH4 to metabolism of retinol to RA.

FIG. 4

All-trans-RA levels were quantitated by HPLC in liver (µg/g) and serum (µg/ml) of WT, Adh1−/−, Adh4−/−, and Adh1/4−/− female mice 2 h after a 50-mg/kg oral dose of all-trans-retinol. All values are from adult female mice (n = 4). Serum RA data for WT, Adh1−/−, and Adh4−/− are also reported previously (20). All values are means ± S.E. *, p < 0.01; **, p < 0.03; *** p < 0.05 (significantly different from the WT value; unpaired Student’s t test).