Figure 1.

Dengue hemorrhage in rhesus monkeys. Rhesus monkeys were intravenously infected with dengue virus as described in “Nonhuman primates, virus, and cells.” Hemorrhagic manifestations were captured with digital camera on days 3 (RM2), 4 (RM4), and 5 (RM3) after infection. Different severity of hemorrhage, ranging from petechiae to severe coagulopathy, was seen. A classic clinical hemorrhage was observed in infected animal RM4. The top and bottom panels indicate that the images of the skin hemorrhage were captured from different parts of the body within the same animal.